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NUCLEODUR® high purity silica phases - meeting highest demands in HPLC
 

Phase

Modification

 % C pH range Particle sizes [µm] USP

C18Gravity

octadecyl, high density coating, multi-endcapping

 18 1–11 1.8 · 3 · 5 L1

C18Gravity-SB

octadecyl (monomeric), extensive endcapping

 13 1–9 1.8 · 3 · 5 L1

C8 Gravity

octyl, high density coating, multi-endcapping

 11 1–11 1.8 · 5 L7

C18 Isis

octadecyl, specially cross-linked modification, endcapped

 20 1–10 1.8 · 3 · 5 L1

C18Pyramid

octadecyl with polar endcapping

 14 1–9 1.8 · 3 · 5 L1

PolarTec

octadecyl with embedded polar group

 17 1–9 1.8 · 3 · 5 L1 L60

Phenyl-Hexyl

special phenylhexyl phase

 10 1–10 1.8 · 3 · 5 L11

PFP

pentafluorophenyl-propyl with multi-endcapping

 8 1–9 1.8 · 3 · 5 L43

Sphinx RP

bifunctional, balanced ratio of propylphenyl and octadecyl, endcapping

 15 1–10 1.8 · 3 · 5 L1 L11

C18 HTec

octadecyl, high density coating, high capacity, multi-endcapping

 18 1–11 1.8 · 3 · 5 
7 · 10		 L1

C18 ec

octadecyl, medium density, endcapping

 17.5
4		 1–9 3 · 5 
and larger		 L1

C8 ec

octyl, medium density, endcapping

 10.5 1–9 3 · 5 L7

C4 ec

butyl, medium density, endcapping

 2.5 1–9 5 L26

HILIC

ammonium – sulfonic acid

 7 2–8.5 1.8 · 3 · 5  

CN/CN-RP

cyano (nitrile) for NP and RP separations

 7 1–8 3 · 5 L10

NH2/NH2-RP

aminopropyl for NP and RP separations

 2.5 2–8 3 · 5 L8

SiOH

unmodified NUCLEODUR®

 – 2–8 3 · 5 
and larger		 L3


NUCLEOSHELL® core-shell silica phases - for highest efficiency HPLC
 

Phase

Modification

 % C Particle size [µm] pH range USP

RP 18

Octadecyl, multi-endcapping

 7.8 2.7 1–11 L1
6.1 5

RP 18plus

Octadecyl (monomeric), multi-endcapping

 5.7 2.7 2–9 L1
4.4 5

Phenyl-Hexyl

Phenyl-Hexyl, multi-endcapping

 4.5 2,7 1–10 L11

PFP

Pentafluorophenyl, multi-endcapping

 ~ 3 2,7 1–9 L43

HILIC

Ammonium – sulfonic acid

 1.3 2,7 2–8.5 –


NUCLEOSIL® standard silica phases - widest choice of modifications
 

Phase

Modification

Formula

RP phases

NUCLEOSIL® C18

medium density octadecyl, endcapped

-(CH2)17-CH3

NUCLEOSIL® C18 AB

crosslinked octadecyl, endcapped, high steric selectivity

-(CH2)17-CH3

NUCLEOSIL® C18 HD

high density octadecyl, endcapped

-(CH2)17-CH3

NUCLEOSIL® C18 Nautilus

hydrophilic octadecyl, embedded polar group, endcapped

-(CH2)17-CH3

NUCLEOSIL® Protect I

special RP phase with protective polar group, endcapped

 

NUCLEOSIL® C8 ec

medium density octyl, endcapped

-(CH2)7-CH3

NUCLEOSIL® C8

standard octyl, not endcapped

-(CH2)7-CH3

NUCLEOSIL® C8 HD

high density octyl, endcapped

-(CH2)7-CH3

NUCLEOSIL® C4

medium density butyl, endcapped

-(CH2)3-CH3

NUCLEOSIL® C2

dimethyl

-(CH3)2

NUCLEOSIL® C6H5

standard phenyl, not endcapped

-(CH2)3-C6H5

Polar phases

NUCLEOSIL® CN

cyanopropyl (nitrile)

-(CH2)3-CN

NUCLEOSIL® OH

diol (dihydroxypropyl)

-(CH2)3-O-CH2-CH(OH)-CH2OH

NUCLEOSIL® NH2

aminopropyl

-(CH2)3-NH2

NUCLEOSIL® N(CH3)2

dimethylamino

-(CH2)3-N(CH3)2

NUCLEOSIL® SA

benzenesulfonic acid, strongly acidic cation exchanger (SCX)

-(CH2)3-C6H4-SO3Na

NUCLEOSIL® SB

quaternary ammonium groups, strongly basic anion exchanger (SAX)

-(CH2)3-C6H4-CH2-N+(CH3)3Cl–

NUCLEOSIL® SiOH

unmodified

(SiO2)n

 
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