Davisil Chromatographic Silica
A wide range of Davisil® silica grades are available from 1kg to multi-ton quantities to meet your application, performance, and economic requirements.
Compared to 60Å silicas traditionally used for small molecule purification, the newly developed 35Å Davisil® silica has higher surface area. This can lead to up to 50% greater loading capacity and 50% reduction in solvent consumption making purification more productive with less impact on the environment.
The 4500Å Davisil® silica grade is especially designed for large molecules commonly purified in bioprocessing.
• Available in both normal phase bare silica and various bonding chemistries (C18, Amino, Diol, Cyano) for alternative selectivity.
• Wide selection of distinct pore diameters
(30Å – 4500Å) for separation of a wide range of MW sizes.
• Available from 1kg to multi-ton quantities.
• Grace not only offers media for process purification but also column hardware, packing equipment, and process HPLC systems for optimized chromatographic performance.
Specifications
| Normal Pore Size |
| Characteristic |
35Å |
60Å |
150Å |
250Å |
500Å |
1000Å |
1500Å |
2500Å |
4500Å |
| Surface Area (m2/g) |
700 |
550 |
330 |
285 |
80 |
40 |
25 |
17 |
10 |
| Pore Volume (mL/g) |
0.6 |
0.9 |
1.2 |
1.8 |
1.1 |
1.1 |
1.1 |
1.1 |
1.1 |
| pH (5% suspension) |
5.7 |
7.3 |
7.3 |
7.5 |
8.0 |
9.0 |
9.0 |
9.0 |
9.5 |
| H2O (weight %)† |
< 6% |
<6% |
<6% |
<6% |
<6% |
<6% |
<6% |
<6% |
<6% |
| Bulk Density (kg/m3) |
720 |
530 |
350 |
210 |
370 |
370 |
370 |
370 |
370 |
†Moisture content (% H20) can be tailored (increased or decreased) to meet customer requirements.
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