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Shiseido的分離管柱，以穩定性高，品質佳著名

以獨特的Capsule Coating技術

讓管柱擁有silica-base及polymer-base共有的優點!

您千萬別錯過!

什麼是資生堂『CAPCELL PAK』呢？

The revolutionary polymer coated “Capsule type” with the combined benefits of the silica gel and polymer types！

SHISEIDO『CAPCELL PAK』的簡介：

CAPCELL PAK columns, manufactured by Shiseido Co., Ltd., Japan, are durable and reproducible HPLC columns designed to eliminate undesirable secondary retention effects, which are commonly observed in conventional silica based columns (e.g., peak tailing).

A two-step synthesis is used: 1) Surface coating of silica, the starting material, with silicone monomers by vapor deposition polymerization (VDP) method, which results in a homogeneous reinforced polymer layer; 2) Introduction of alkyl groups to the coated surface. This process provides excellent peak shapes for acidic, basic and chelating compounds. Three types of CAPCELL PAK columns-UG、MG、MF-are available in different sizes, ranging from analytical to preparative scale.

SHISEIDO『CAPCELL PAK』與其他種類Column的比較：

	Silica Type	Shiseido Capsule Type	Polymer Type
Pressure durability	○ (20MPa)	○ (20MPa)	×(3.5~7MPa)
Alkaline resistance	△ (pH2-7)	○ (pH2-10)	◎ (pH1-12)
Separation	○	◎	△
Validation	○	◎	×

SHISEIDO『CAPCELL PAK』的特性：

高純度Silica、低金屬含量

適用pH範圍甚廣(pH2-10)

低壓力

檢附原廠保證書

不會造成TAILING、提昇peak對稱性

提供C18、C8、C1、ph、CN、NH2、SCX固定相

secondary retention effects降至最低

GLP/GMP-supporting columns

excellent lot-to-lot reproducibility

CAPCELL PAK MG系列另針對有機化合物提昇分析效果，延長滯留時間。

資生堂『CAPCELL PAK』系列各式管柱簡介

1. Capcell pak MF column

MF column的特色：

減少樣品繁雜的前處理程序，提高回收率：您只需將樣品過濾即可上機分析，便可分離蛋白質與微量待測品；省卻了繁複的蛋白質沉澱、離心、濃縮、溶洗等步驟。

適用於血清、血漿、血液、尿液、植物或動物組織萃取液中的藥物、藥物代謝物、peptides或其他微量化合物之分析﹔食品、飲品之微量待測物分析。

Analysis of Low-Concentration Drugs in Serum and Plasma by MF & UG columns (Dual Column System)

Analysis of Low-Concentration Drugs in Serum and Plasma by MF & UG columns (Triple Column System)

2. Capcell pak UG、MG column

(A) 極低金屬含量

(B) 適用pH範圍甚廣：移動相或樣品的pH範圍介於pH2~pH10之間皆可放心使用無虞。

(D) 不造成TAILING：另經Endcapping程序，給予column良好品質，並對於silanol基提升有效的去活性化，將Tailing的機率降至最低。CAPCELL PAK MG系列分析管柱更提昇peak對稱性。

(E) 檢附原廠保證書。

(F) 提供多種Phases：C18、C8、C1、phenyl、CN、NH2、SCX

(G) 提供數種Pore Size：80 Å、100 Å、120 Å、300Å

(H) 提供數種粒徑：3μm、5μm…

( I ) CAPCELL PAK MG系列另針對有機化合物提昇分析效果。

3. Capcell pak ACR column

最精純的silica

pH1-10 Guaranteed

可長時間run pH極低的移動相或樣品

Peak對稱性優良

檢附原廠報告

適用於一般分析或鹼性樣品分析

Shown below is a good profile of 5 tricyclic antidepressants, separated under a typical condition (utilizing formic acid) for LC/MS analysis.

4. Capcell pak C18 AQ column

For the analysis of highly polar compounds

可長時間使用100%水相移動相

應用於分析高極性化合物，如有機酸類或藥品

pH range 2-9

以精純silica鍵結C18後被覆polymer，保護脆弱

　　的C18不受水相影響而斷裂。