Quadrex 一般型GC毛細分離管簡介 :

－ Bonded and Crosslinked

－ Non-polar ~ Very polar columns

－ Several types are provided with excellent 

    thermal stability

■ 007-1

   Dimethylpolysiloxane

The non-polar dimethylpolysiloxane phase, which separates compounds according to boiling point, is probably the most frequently used phase type in GC. Bonding and crosslinking this general purpose GC phase increases the resistance to degradation by rinsing, large solvent injections and the deposition of non-volatiles. The 007-1 phase offers excellent efficiency and thermal stability. In addition, this non-polar phase is less susceptible to oxidation and hydrolysis than phases incorporating more polar functional groups.

■ 007-5

    (5% Phenyl) Methylpolysiloxane

The 007-5 is a non- polar 5% phenyl methylpolysiloxane polymer, and is a widely used general purpose GC phase ideal for a broad range of applications. The presence of the phenyl groups provides induced dipole interactions leading to degrees of increased retention for aromatic solutes. The 5% phenyl substitution causes a nominal increase in polarity.

■ 007-10, 007-20

   (10% and 20% Phenyl) Methylpolysiloxane

The 007-10 and 007-20 are (10% phenyl) and (20% phenyl) substitutions, respectively, for two low polarity phenyl methylpolysiloxane phases. The phenyl substitutions contribute to the “induced dipole” selectivity of these phases. A column coated with either phase displays excellent efficiency and thermal stability. These phases provide an excellent alternative for drug and environmental pollutant analyses where greater retention of aromatic compounds is necessary.

■ 007-502, 007-608, 007-624

   Cyanopropylphenyl Methylpolysiloxane

007-502, 007-608, and 007-624 are three slightly different versions of cyanopropylphenyl substitutions on a methylpolysiloxane phase backbone. These phases have been specifically designed for difficult environmental analyses, such as volatile organic compounds and pesticides as specified in many EPA Methods including 502.1, 502.2, 503.1, 524.1, 524.2, 601, 602, 608, 624, 8010, 8011, 8015, 8020, 8240, and 8260. By using 007-502 and 007-624 phase types on 0.53mm I.D. columns, the entire range of volatile compounds, including gases, can be analyzed beginning at ambient temperatures. 

■ 007-210

   (50% Trifluoropropyl) Methylpolysiloxane

007-210 is the Quadrex designation for a (50% trifluoropropyl) methylpolysiloxane (moderately polar). The trifluoropropyl groups of the 007-210 phase act as strong electron acceptors and provide a unique retention for carbonyls over other oxygenated functional groupings. Increased retention for oxygenated compounds is in the order of ether, hydroxy, ester and keto. Historically, the unique retention characteristics of the trifluoropropyl polysiloxanes were utilized for steroid analyses; but chlorinated pesticides, PCB’s, organophosphate pesticides, phenols and nitroaromatics are also good candidates for separation with 007-210 columns.

■  007-225

   (50% Cyanopropylphenyl) Methylpolysiloxane

007-225 is a moderately polar (50% cyanopropylphenyl) methylpolysiloxane. This phase possesses both permanent dipole interactions (nitrile) as well as induced dipole (phenyl) and dispersion interactions. It has unique selectivity for derivatized compounds such as fatty acids and carbohydrates. Non-volatile residues can be rinsed from the column to restore column performance.

■  007-23

   (78% Cyanopropyl) Methylpolysiloxane

007-23 is a (78% cyanopropyl) methylpolysiloxane and is our most polar phase type. The strong permanent dipole interactions of this phase with unsaturated compounds yields separations according to geometric configurations of the double bonds. The 007-23 phase is ideal for the separation of cis/trans isomers of fatty acid methyl esters (FAMEs) as well as the isomers of dioxins and furans. The 007-23 phase is bonded and crosslinked and the column performance can be restored by rinsing.

■ 007-17

   (50% Phenyl) Methylpolysiloxane

007-17 is a medium polar (50% phenyl) methylpolysiloxane phase. The presence of the 50% phenyl groups increases the overall “polarity” of the phase and enhances the selectivity of induced dipole interactions resulting in greater retention of aromatic solutes. The 007-17 phase is widely used as an EPA Method confirmation column and provides for efficient separations of PAH’s, and biomedical samples such as drugs, sugars and steroids.

■ 007-1301

   (6% Cyanopropylphenyl) Methylpolysiloxane

007-1301 is a moderately polarity phase which exhibits excellent thermal stability. The cyanopropyl (permanent dipole) and the phenyl (polarizable) substituents provide a specific selectivity for polar and polarizable compounds. Nitrogen-containing herbicides, various types of pesticides, drugs and other heteroatom-containing compounds are good candidates for separation using this phase. As part of the 007 Series of bonded phases, the 007-1301 can withstand large solvent injections and rinsing to remove insoluble impurities.

■ 007-35

   (35% Phenyl) Methylpolysiloxane

007-35 is the Quadrex designation for a (35% phenyl) methylpolysiloxane phase. This phase is a compromise between 007-20 and 007-17 in phenyl content. It is a popular phase for drug and pesticide/herbicide analyses; and like the entire series of phenyl-substituted phases, columns coated with the 007-35 can be rinsed to remove nonvolatile and high boiling contaminants.

■ 007-1701

   (14% Cyanopropylphenyl) Methylpolysiloxane

007-1701 is a moderately polar (14% cyanopropylphenyl) methylpolysiloxane phase. The cyanopropyl functional groups provide a permanent dipole selectivity different from the induced dipole interactions of the phenyl groups. The overall “polarity” of this phase remains nominal when compared to the more highly cyanopropyl substituted phases such as 007-225 and 007-23. The 007-1701 phase is often used for solvents, pharmaceuticals, derivatized sugars and many environmental applications.

■ 007-65HT, 400-65HT

   (65% Phenyl) Methylpolysiloxane

007-65HT and 400-65HT phases represent a (65% phenyl) methylpolysiloxane phase composition (moderately polar). 007-65HT is a bonded phase, which possesses excellent thermal stability and hence can be used routinely for high temperature analyses. The 400-65HT is the identical phase, which we offer on aluminum-clad tubing. Since the polyimide outer coating on standard columns begins to degrade at 380-400℃, the aluminum-clad tubing offers slightly longer column lifetime if the column is intended to be used at the elevated temperatures. This enhanced selectivity is most evident in the analysis or triglycerides where the resolution is “fine tuned” over that of the 50% phenyl substitution. Examples of the improved resolution of the ‘65HT’ phases are shown in the Triglyceride Section.